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New Dual Small Molecules for Alzheimer’s Disease Therapy Combining Histamine H 3 Receptor (H3R) Antagonism and Calcium Channels Blockade with Additional Cholinesterase Inhibition

Rim Malek Raquel Arribas Alejandra Palomino-Antolin Perle Totoson Celine Demougeot Tereza Kobrlova Ondrej Soukup Isabel Iriepa Ignacio Moraleda Daniel Diez-Iriepa Justyna Godyń Dawid Panek Barbara Malawska Monika Głuch-Lutwin Barbara Mordyl Agata Siwek Fakher Chabchoub José Marco-Contelles Katarzyna Kiec-Kononowicz Javier Egea Cristóbal de los Ríos Lhassane Ismaili 1
1 Laboratoire de Recherches Intégratives en Neurosciences et Psychologie Cognitive, Université de Bourgogne - Franche-Comté, Besançon, France.
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https://hal-univ-fcomte.archives-ouvertes.fr/hal-03654642
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Submitted on : Thursday, April 28, 2022 - 5:12:12 PM
Last modification on : Friday, April 29, 2022 - 3:08:35 AM

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UNIV-FCOMTE | UNIV-BOURGOGNE

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Rim Malek, Raquel Arribas, Alejandra Palomino-Antolin, Perle Totoson, Celine Demougeot, et al.. New Dual Small Molecules for Alzheimer’s Disease Therapy Combining Histamine H 3 Receptor (H3R) Antagonism and Calcium Channels Blockade with Additional Cholinesterase Inhibition. Journal of Medicinal Chemistry, American Chemical Society, 2019, 62 (24), pp.11416-11422. ⟨10.1021/acs.jmedchem.9b00937⟩. ⟨hal-03654642⟩

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