Genetic risk factors for the posterior cortical atrophy variant of Alzheimer's disease

Jonathan Schott , Sebastian Crutch , Minerva Carrasquillo , James Uphill , Tim Shakespeare , Natalie Ryan , Keir Yong , Manja Lehmann , Nilufer Ertekin-Taner , Neill Graff-Radford , Bradley Boeve , Melissa Murray , Qurat Ul Ain Khan , Ronald Petersen , Dennis Dickson , David Knopman , Gil Rabinovici , Bruce Miller , Aida Suárez González , Eulogio Gil-Néciga , Julie Snowden , Jenny Harris , Stuart Pickering-Brown , Eva Louwersheimer , Wiesje van Der Flier , Philip Scheltens , Yolande Pijnenburg , Douglas Galasko , Marie Sarazin , Bruno Dubois , Eloi Magnin (1) , Daniela Galimberti , Elio Scarpini , Stefano Cappa , John Hodges , Glenda Halliday , Lauren Bartley , Maria Carrillo , Jose Bras , John Hardy , Martin Rossor , John Collinge , Nick Fox , Simon Mead , Nilufer Ertekin‐taner , Neill Graff‐radford , Eulogio Gil‐néciga , Stuart Pickering‐brown , Wiesje Flier

1 UFC - Université de Franche-Comté

The genetics underlying posterior cortical atrophy (PCA), typically a rare variant of Alzheimer's disease (AD), remain uncertain.

Keywords: APOE; Alzheimer's disease; GWAS; Genetics; Posterior cortical atrophy; Selective vulnerability

Domains: Life Sciences [q-bio]

Jonathan Schott, Sebastian Crutch, Minerva Carrasquillo, James Uphill, Tim Shakespeare, et al.. Genetic risk factors for the posterior cortical atrophy variant of Alzheimer's disease. Alzheimer's & Dementia , 2016, 12 (8), pp.862-871. ⟨10.1016/j.jalz.2016.01.010⟩. ⟨hal-03630220⟩