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Soluble TNF-R1, but not tumor necrosis factor alpha, predicts the 3-month mortality in patients with alcoholic hepatitis

Abstract : In alcoholic hepatitis (AH), soluble TNF alpha receptor-1 (sTNF-R1) is increased. Elevated TNF alpha predicts mortality, but infection influences TNF alpha values. In patients with AH, we determined the prognostic value of TNF alpha, sTNF-R1, and lipopolysaccharide binding protein (LBP) and CD14, both involved in endotoxemia-associated inflammation.
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https://hal-univ-fcomte.archives-ouvertes.fr/hal-03537119
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Submitted on : Thursday, January 20, 2022 - 11:33:31 AM
Last modification on : Friday, January 21, 2022 - 3:08:01 AM

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Laurent Spahr, Emile Giostra, Jean-Louis Frossard, Solange Bresson-Hadni, Laura Rubbia-Brandt, et al.. Soluble TNF-R1, but not tumor necrosis factor alpha, predicts the 3-month mortality in patients with alcoholic hepatitis. Journal of Hepatology, Elsevier, 2004, 41 (2), pp.229-234. ⟨10.1016/j.jhep.2004.04.028⟩. ⟨hal-03537119⟩

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