Rapid detection of colistin resistance in Acinetobacter baumannii using MALDI-TOF-based lipidomics on intact bacteria

Laurent Dortet (1, 2, 3) , Anaïs Potron (4, 5) , Rémy A. Bonnin (2) , Patrick Plésiat (4, 5) , Thierry Naas (2) , Alain Filloux (1) , Gérald Larrouy-Maumus (1)

1 MRC CMBI - Medical Research Council Centre for Molecular Bacteriology and Infection [Londres, Royaume-Uni]
2 Hôpital Bicêtre [AP-HP, Le Kremlin-Bicêtre]
3 Faculté de Médecine Paris Sud, Le Kremlin-Bicêtre
4 CNR - Centre National de Référence de la Résistance aux Antibiotiques
5 Service de bactériologie [Besançon]

Nineteen Proteus mirabilis isolates producing the carbapenemase OXA-23 were recovered over a 2-year period in 19 French hospitalized patients, of whom 12 had community onset infections. The isolates exhibited a slightly reduced susceptibility to carbapenems.

Domaines: Microbiologie et Parasitologie

Laurent Dortet, Anaïs Potron, Rémy A. Bonnin, Patrick Plésiat, Thierry Naas, et al.. Rapid detection of colistin resistance in Acinetobacter baumannii using MALDI-TOF-based lipidomics on intact bacteria. Scientific Reports, 2018, 8 (1), pp.669-673. ⟨10.1038/s41598-018-35041-y⟩. ⟨hal-03505776⟩