Evaluation of the Immunochromatographic NG-Test Carba 5 for Rapid Identification of Carbapenemase in Nonfermenters

Pauline Triponney (1) , Anaïs Potron (1) , Thierry Naas (2, 3) , Laurent Dortet (2, 3) , Damien Fournier (1) , Patrick Plésiat (1) , Cécile Emeraud (2)

1 CNR - Centre National de Référence de la Résistance aux Antibiotiques
2 Hôpital Bicêtre [AP-HP, Le Kremlin-Bicêtre]
3 French National Reference Center for Antibiotic Resistance: Carbapenemase producing Enterobacteriaceae [Le Kremlin-Bicêtre]

The immunochromatographic assay NG-Test Carba 5 (NG-Biotech) was evaluated with a collection of 107 carbapenemase-producing nonfermenters (CP-NF) (55 Pseudomonas spp., 51 Acinetobacter spp., and 1 Achromobacter xylosoxidans isolate) and 61 carbapenemase-negative isolates. All KPC, VIM, and NDM carbapenemase producers tested were accurately detected. Of the 16 IMP variants tested, 6 (37.5%) variants were not detected.

Domaines: Microbiologie et Parasitologie

Pauline Triponney, Anaïs Potron, Thierry Naas, Laurent Dortet, Damien Fournier, et al.. Evaluation of the Immunochromatographic NG-Test Carba 5 for Rapid Identification of Carbapenemase in Nonfermenters. Antimicrobial Agents and Chemotherapy, 2019, 63 (9), pp.1469-1472. ⟨10.1128/AAC.00968-19⟩. ⟨hal-03505678⟩