Cortical modulation of nociception by galvanic vestibular stimulation: A potential clinical tool?

Koichi Hagiwara , Caroline Perchet (1) , Maud Frot (2) , Hélène Bastuji (2) , Luis Garcia-Larrea (1)

1 INSERM E342
2 NEUROPAIN - Central Integration of Pain in Human

Vestibular afferents converge with nociceptive ones within the posterior insula, and can therefore modulate nociception. Consistent with this hypothesis, caloric vestibular stimulation (CVS) has been shown to reduce experimental and clinical pain. Since CVS can induce undesirable effects in a proportion of patients, here we explored an alternative means to activate non-invasively the vestibular pathways using innocuous bi-mastoid galvanic stimulation (GVS), and assessed its effects on experimental pain.

Mots clés: Anti-nociception; Galvanic vestibular stimulation; Painful laser; Posterior insula

Domaines: Neurosciences [q-bio.NC]

Koichi Hagiwara, Caroline Perchet, Maud Frot, Hélène Bastuji, Luis Garcia-Larrea. Cortical modulation of nociception by galvanic vestibular stimulation: A potential clinical tool?. Brain Stimulation, 2020, 13 (1), pp.60-68. ⟨10.1016/j.brs.2019.10.009⟩. ⟨hal-02472461⟩